Nicotinic Acetylcholine Receptor: Structure and Function by Alfred Maelicke (Eng

Description: Nicotinic Acetylcholine Receptor by Alfred Maelicke Estimated delivery 3-12 business days Format Paperback Condition Brand New Description Proceedings of the NATO Advanced Research Workshop on Mechanism of Action of the Nicotinic Acetylcholine Receptors held on the Island of Santorini, Greece, May 19-23, 1986 Publisher Description The most critical event in chemical cell to cell communications is the conversion of the chemical signal into the primary response of the receiving cell. In the case of cholinergic cell to cell communication, i. e. in cholinergic nerve-nerve and nerve- muscle systems, a single molecule, namely the nicotinic acetyl- choline receptor is responsible for both signal reception and primary response: Through binding of the neurotransmitter acetyl- choline released from the associated nerve ending, the receptor receives the chemical message. Short-lived openings of the recep- tor-integral ion channel constitute the initial reaction to this stimulation, i. e. the primary response. This integration of the receiving and the responsive unit into a single protein structure seems to be typical for transmi tter-acti vated ion channel pro- teins of many excitable cells including those of the central ner- vous system. Elucidation of the mechansim of action of the acetylcholine receptor is of interest, therefore, not only for cholinergic cell to cell communications but, even more impor- tantly, as a general model for the less accessible neurotransmit- ter receptors of the central nervous system.While the basic reactions in the, course of cholinergic cell to cell communication and the molecular components involved are rather well understood, a molecular mechanism for cholinergic ex- ci tation has not yet been established. Details ISBN 3642716512 ISBN-13 9783642716515 Title Nicotinic Acetylcholine Receptor Author Alfred Maelicke Format Paperback Year 2011 Pages 492 Publisher Springer-Verlag Berlin and Heidelberg GmbH & Co. KG GE_Item_ID:151490678; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

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